Mast Cell Activation Syndrome (MCAS) is a condition characterized by inappropriate mast cell activation, leading to a range of symptoms that can affect multiple systems in the body. Individuals with MCAS may experience symptoms such as hives, gastrointestinal issues, and respiratory problems. These symptoms can vary widely, making diagnosis challenging.
Mast cells play a crucial role in the immune system, helping to protect the body from pathogens. However, in MCAS, these cells can become overactive, releasing excessive amounts of histamine and other chemicals. This overactivity can lead to a variety of allergic-like symptoms.
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Management of MCAS often involves identifying triggers and avoiding them. Medications such as antihistamines may also be prescribed to help control symptoms.